An exhausted elephant had died after trudging a mammoth 1,700km after becoming separated from her herd by floods.
The mammal that was distressed made the incredible journey between India and Bangladesh on Tuesday.
She was discovered washed across the boundary in late June and treated by specialists who tranquillised her three times in an attempt to transport her to a Bangladeshi safari park.
But despite being treated with massive numbers of saline and chained in a paddy field to help her recuperate, she was “too feeble and exhausted” from her ordeal, officials said.
“It breathed its last at around 7am (0100 GMT),” the government’s leader wildlife conservator Ashit Ranjan Paul told AFP.
“We’ve given our best effort to save the creature. At least 10 forest rangers, vets and policemen have constantly followed it for the last 48 days. But our chance is poor,” he said.
Mr Paul believed the creature came in the northeastern Indian state of Assam, but when she reached Bangladesh she ran and charged into a pond.
Local villagers saved the four-tonne creature by stopping her from toppling into the water from drowning, but a mahout was injured during another rescue attempt on Monday.